Articles - Anti-Depressants

Antidepressants Effect on Brain States
 
Antidepressants are assumed to work on the specific neurobiology of depressive disorders according to a “disease-centered” model of drug action. However, little evidence supports this idea. An alternative, “drug-centered,” model suggests that psychotropic drugs create abnormal states that may coincidentally relieve symptoms. Drug-induced effects of antidepressants vary widely according to their chemical class—from sedation and cognitive impairment to mild stimulation and occasionally frank agitation. Results of clinical trials may be explained by drug-induced effects and placebo amplification. No evidence shows that antidepressants or any other drugs produce long-term elevation of mood or other effects that are particularly useful in treating depression.

Do Antidepressants Cure or Create Abnormal Brain States?
 
Antidepressants are assumed to work on the specific neurobiology of depressive disorders according to a “disease-centred” model of drug action. However, little evidence supports this idea. An alternative, “drug-centred,” model suggests that psychotropic drugs create abnormal states that may
coincidentally relieve symptoms.   
 
The Dangers of Prozac, Part 1
 
 A look at what this popular antidepressant drug side effects are.
 
The Dangers of Prozac, Part 2
 
Depression, Sexual Dysfunction and Acute Dystonia are some conditions discussed.